Stiffness measurement using terahertz and acoustic waves for biological samples

Yoon J.-H., Yang Y.-J., Park J., Son H., Park H., Park G.-S., Ahn C.-B.
Optics Express, 23(25), 32671(2015)
DOI: 10.1364/OE.23.032671

Abstract

A method is proposed to measure sample stiffness using terahertz wave and acoustic stimulation. The stiffness-dependent vibration is measured using terahertz wave (T-ray) during an acoustic stimulation. To quantify the vibration, time of the peak amplitude of the reflected T-ray is measured. In our experiment, the T-ray is asynchronously applied during the period of the acoustic stimulation, and multiple measurements are taken to use the standard deviation and the maximum difference in the peak times to estimate the amplitude of the vibration. Some preliminary results are shown using biological samples. © 2015 Optical Society of America.