Correlation between salt-induced change in water structure and lipid structure of multi-lamellar vesicles observed by terahertz time-domain spectroscopy

Choi D.-H., Son H., Jeong J.-Y., Park G.-S.
Chemical Physics Letters, 659, 164(2016)
DOI: 10.1016/j.cplett.2016.07.031

Abstract

Salt-induced change in the structure of water molecules inside multi-lamellar vesicles is experimentally studied with terahertz time-domain spectroscopy. The complex dielectric constant of 1, 2-ditetradecanoyl-sn-glycero-3-phosphocholine model membranes dispersed in NaCl solution with different salt concentrations are measured. Structure of water molecules in the solution is characterized from the measured dielectric constant using Debye relaxation model. Combined with small-angle X-ray scattering observation, it is found that salt-induced change of water structure, especially fast water fraction, show strong correlation with the increase in nanometer-scale multi-lamellar repeat space. This suggests that water could be critical in nanometer-scale membrane-membrane communications. © 2016 Elsevier B.V.